Toxicology is the study of the adverse effects of chemical or biological agents on living organisms. Data generated from toxicological studies may help estimate the toxicological characteristics of an agent under specific conditions of exposure. These data are in turn critical to estimating and managing risks associated with past, present, or future exposures. Whether a toxic response occurs depends upon such factors as the chemical, biological, and physical properties of the agent, how the agent is metabolized by the organism, and the overall susceptibility of the organism. Other factors include the route of administration of the agent, and the duration and frequency of the exposure. Impacted individuals may include workers, consumers, the general public, or sensitive populations such as children, the elderly, and the sick.
Intertox & Toxicology
Intertox professionals are trained in interpreting and critically evaluating toxicological data for our clients. We also have expertise in designing and conducting toxicological studies when existing data are insufficient or inadequate to solve problems. Intertox works closely with clients to understand their goals and needs and to help direct our toxicological investigations. Typically, our work will be used to assess the potential toxicity of a chemical or biological agent in the environment or in new or existing products. Intertox obtains as much information as possible at the beginning of every project to assign an appropriate level of effort to each investigation, thereby using client resources efficiently.
Our Toxicology Specialties
Intertox professionals are well-versed in a wide range of toxicological disciplines, but specialize in the following three areas:
Neurotoxicology
Neurotoxicology focuses on adverse effects in the brain or nervous system, such as visual and speech disturbances, delirium, convulsions, and encephalopathy.
Reproductive and Developmental Toxicology
Reproductive toxicology focuses on effects that are adverse to reproductive fitness, such as alterations in sexual behavior, menstrual disorders, and low sperm count. Developmental toxicology focuses on effects that are adverse to the developing organism, such as birth defects, spontaneous abortion, and developing behavioral deficits.
Regulatory Toxicology
Toxicology studies are often conducted specifically to fulfill federal, state, or local regulatory agency requirements. The Intertox team not only understands the technical issues involved in this process, but offers a firm grounding in science to assist in negotiating with agencies.