Richard C. Pleus, Ph.D., Director

Intertox is pleased to provide the second edition of our 2007 Nanotechnology EHS newsletter. We are dedicated to providing relevant and current information regarding environmental health and safety (EHS) risks associated with nanoparticles, nanomaterials, and processes of nanotechnology. This newsletter will guide you to the most important developing news and information in this rapidly expanding field. Intertox has developed a nanotechnology EHS team to address issues that may impact public health, including EHS, legal and worker safety concerns, and risk management. We are involved with numerous projects in this quickly developing field and are ready to assist consumers, businesses, agencies, researchers, and policy-makers that need access to current and relevant publications, news, and events.

Intertox is currently involved with many projects and committees regarding the field of nanotechnology. We actively support current regulatory EHS developments, and have made numerous presentations on nanotechnology at conferences across the country. The EHS related projects we are currently working on include assessments of consumer products, lifespan of nanomaterials, and occupational exposures. Our clients range from consulting services to large multi-national corporations. On top of these exciting projects, Intertox is currently assisting in the development of science-based guidelines and standards related to nanotechnology EHS through our membership and participation with the American National Standards Institute (ANSI) Technical Advisory Group.

Let us know how we can help to keep you better informed of the emerging developments concerning nanotechnology. We can provide timely, informed assessments of this information and its potential impact on your business or agency. Also, please e-mail us your feedback, as we welcome your comments and suggestions about how we might improve this service. If you wish to be deleted from distribution of future newsletters, please click here.

"Planning now can reduce risks of environmental and health-related side effects"
PressZoom, February 20, 2007

"Area scientists to study safety of nanomaterials"
Jim DeBrosse, Dayton Daily News, February 19, 2007

"Green chemistry can help nanotechnology"
Science Daily, February 19, 2007

"Proprietary Testing Won't Convince Public of Nanotechnology's Safety, Says Head of Texas Group"
NanoTechWire, February 16, 2007

California
"Batten Down The Hatches Against HIV: Carbon Nanotubes Transport Gene Therapy Drug Into T-cells"
Science Daily, February 21, 2007

"The Nanoethics Group to Speak at Cal/EPA Nanotechnology Symposium"
Nanovip.com, February 20, 2007

Illinois
"USP Chapter 797: One of New Contamination Control: Topics at ESTECH 2007"
Nanotech Now, February 15, 2007

"On discussing nanotechnology with transhumanists"
Nanowerk News, January 29, 2007

Massachusetts
"Nanotech success requires manufacturing research"
Reliable Plant, February 8, 2007

"Nanotechnology Will Turn Science Fiction Into Reality"
Tech News Daily, January 27, 2007

Michigan
"WMU Innovation projects"
Kalamazoo Gazette, February 15, 2007

"Recent developments announced by University of Michigan, U.S."
NewsRx.com, February 8, 2007

New York
"Nanoparticles advance photodynamic therapy to kill tumor cells"
Medical Science News, February 7, 2007

"Quantum Biology: Powerful Computer Models Reveal Key Biological Mechanism - 2007-01-30"
Exduco, January 30, 2007

Ohio
"American Nanotechnology Researcher Recruited to Canada"
Nanotechnology Now, February 18, 2007

"Ohio improves in nano ranking"
Ohio.com, February 3, 2007

Texas
"Consumer Confidence a 'Paramount Concern' in Growth of Nanotechnology, According to Former Texas Official"
nanotechwire.com, February 8, 2007

"Promise of Nanotechnology Depends on Testing, Safety Standards"
nanotechwire.com, January 27, 2007

Virginia
"Luna Innovations Awarded $4 Million in Air Force Nanotechnology Contracts"
Nanovip.com, January 22, 2007

"HB 2275 Nanotechnology Authority Act of 2007; created, report"
State Legislative, January, 2007

Africa
"Isoun takes practical technology to Africa"
Chris Uwaje, Vanguard, February 14, 2007

"UN Calling For More Regulation Of Nanotechnology"
Manufacturing.Net, February 5, 2007

Asia
"Ramamurthy Calls for PPP Model for Nano Technology Application"
SDA Asia, February 19, 2007

"Safety should be guaranteed in nanotechnology: expert"
Xinhua, February 19, 2007

"China Holding Nanotechnology To Dominate The Scientific World - Report"
Nanotechwire.com, February 17, 2007

"Targeting bladder tumor cells in vivo and in the urine with a peptide identified by phage display"
Medical Research News, February 12, 2007

Australia and Oceania
"Australian expertise showcased at Nanotech Japan"
QBR, February 20, 2007

Europe
"Nanotechnology and health care multimedia file"
Nanowerk News, February 16, 2007

"In Denmark, nanotechnology risk research is part of food science"
Nanowerk News, February 16, 2007

"German company takes proactive approach to nanotechnology safety"
Nanowerk News, January 29, 2007

""Less is more": New diagnostics with nanometer-sized particles"
uni-protokolle.de, January 23, 2007

"Citizens find nanotechs 'elitist'"
EurActiv.com, January 23, 2007

Middle East
"New nanotech centre attracts researchers back to Turkey"
CORDIS, February 15, 2007

North and Central America
"Nanotechnology Inches Its Way Into Classrooms"
February 4, 2007

"Groundbreaking Canadian nanotechnology partnership lays foundation for big success from tiny tech"
Nanotechwire, February 17, 2007

South America
"Nanotech Leades ro Explore Paths from Research Lab to Marketplace"
Arizona Biotech News, February 20, 2007

"Latin America 'ripe for regional collaboration'"
SciDev.Net, February 2, 2007

"Notice of Availability of the Final Nanotechnology White Paper"
US EPA, February 15, 2007

"Risk research is part of the U.S. government's 2008 nanotechnology budget"
Nanowerk News, February 9, 2007

"Public Shares Views on Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials"
Nanotechwire.com, January 10, 2007

"EPA’s Science Policy Council has issued the Nanotechnology White Paper (EPA/100/B-07/001, February 2007): EHS Public Meeting Transcript; EHS Public Meeting Presentations; EHS Public Meeting: Submitted Comments"
National Nanotechnology Coordination Office, January 4, 2007

"Nanotechnologies and nanosciences: a discussion on ethical, legal and social aspects [PDF]"
DG Research European Commission, NanoDialogue Consortium, February 5, 2007

"Report outlines vision for nanomedicine in Europe"
CORDIS, February 1, 2007

"Ethics group publishes opinion on nanomedicine"
CORDIS, January 29, 2007

Joint EFCOG/DOE Chemical Management Workshop: Chemical Safety and Life Cycle Management
DOE Forrestal Auditorium (GE-086), March 13 - 15, 2007

2nd Annual Nanotechnology & the Life Sciences 2007
National Heart Lung and Blood Institute (NHLBI),National Cancer Institute (NCI), Washington University Medical Center in St. Louis, MO, March 30 - 31, 2007

2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual
NSTI, Santa Clara Convention Center May 20-24, 2007

SETAC Europe 2007
Society of Environmental Toxicology and Chemistry (SETAC), Congress and Exhibition Centre in Porto, Portugal, May 20-24, 2007

AIHce 2007
American Industrial Hygiene Association, June 2-7, 2007

Functionalized Nanoscale Materials, Devices, and Systems for chem.-bio Sensors, Photonics, and Energy Generation and Storage
NATO-Advance Study Institute, Sinaia, Romania, June 4-15, 2007

EuroNanoforum 2007: Nanotechnology in Industrial Applications
VDI Technologiezentrum GmbH, CCD Düsseldorf, Germany, June 19-21, 2007

Cancer Nanotech
Upper Side Conferences, Paris, June 26 - 28, 2007

CSL / JIFSAN Joint Symposium on Food Safety and Nutrition: Nanotechnology in Foods and Cosmetics
Joint Institute for Food Safety and Applied Nutrition (JIFSAN), Central Science Laboratory (CSL),, Greenbelt Marriott, Greenbelt, MD, June 26 - 28, 2007

Nano Toxicity Conference 2007
JUpper Side Conferences, Sofitel Bercy, Paris France, June 26-28, 2007

SBE's 3rd International Conference on Bioengineering and Nanotechnology
Society for Biological Engineering (SBE), Biopolis, Singapore, August 12-15, 2007

3rd International Symposium on Nanotechnology, Occupational and Environmental Health
Nanoscience and Technology Program, International Conference Hall, Academia Sinica, Taipei, Taiwan, Auguts 29 - September 1, 2007

International Symposium on Nanotechnology in Environmental Protection and Pollution, ISNEPP 2007
Asia Pacific Nanotechnology Forum, Bahia Mar Beach Resort & Yachting Center, 801 Seabreeze Boulevard, Fort Lauderdale, FL, December 11 - 13, 2007

Worldwide Emerging Environmental Issue Affecting the U.S. Military: January 2007 Report [PDF]
Battelle Columbus Operations, U.S. Army Environmental Policy Institute, 2007

Nanotechnology’s Invisible Threat [PDF]
Natural Resources Defense Council, January 23, 2007

Extreme Genetic Engineering: ETC Group Releases Report on Synthetic Biology [PDF]
ETC Group, January 1, 2007

Balbus JM, Florini K, Denison RA, and Walsh SA. 2007. Protecting workers and the environment: An environmental NGO's perspective on nanotechnology. Journal of Nanoparticle Research V9 (1):11-22.

Cho SJ, Maysinger D, Jain M, Roder B, Hackbarth S, and Winnik FM. 2007.Long-Term Exposure to CdTe Quantum Dots Causes Functional Impairments in Live Cells. Langmuir 23 (4):1974-1980.

Choi AO, Cho SJ, Desbarats J, Lovric J, and Maysinger D. 2007. Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells. J Nanobiotechnology 5 (1):1.

Du D, Huang X, Cai J, Zhang A, Ding J, and Chen S. 2007. An amperometric acetylthiocholine sensor based on immobilization of acetylcholinesterase on a multiwall carbon nanotube-cross-linked chitosan composite. Anal Bioanal Chem387 (3):1059-65.

Duffus JH. 2007. Carcinogenicity classification of vanadium pentoxide and inorganic vanadium compounds, the NTP study of carcinogenicity of inhaled vanadium pentoxide, and vanadium chemistry. Regul Toxicol Pharmacol 47 (1):110-4.

Fissan H, Neumann S, Trampe A, Pui DYH, and Shin WG. 2007. Rationale and principle of an instrument measuring lung deposited nanoparticle surface area. Journal of Nanoparticle Research V9 (1):53-59.

Gao J, Liang G, Zhang B, Kuang Y, Zhang X, and Xu B. 2007. FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells. J Am Chem Soc 129 (5):1428-33.

Hyung H, Fortner JD, Hughes JB, and Kim J-H. 2007. Natural Organic Matter Stabilizes Carbon Nanotubes in the Aqueous Phase. Environ. Sci. Technol. 41 (1):179-184.

Japuntich DA, Franklin LM, Pui DY, Kuehn TH, Kim SC, and Viner AS. 2007. A comparison of two nano-sized particle air filtration tests in the diameter range of 10 to 400Â nanometers. Journal of Nanoparticle Research V9 (1):93-107.

Kamruzzaman Selim KM, Ha YS, Kim SJ, Chang Y, Kim TJ, Ho Lee G, and Kang IK. 2007. Surface modification of magnetite nanoparticles using lactobionic acid and their interaction with hepatocytes. Biomaterials 28 (4):710-6.

Kandlikar M, Ramachandran G, Maynard A, Murdock B, and Toscano WA. 2007. Health risk assessment for nanoparticles: A case for using expert judgment. Journal of Nanoparticle Research V9 (1):137-156.

Keller KH. 2007. Nanotechnology and society. Journal of Nanoparticle Research V9 (1):5-10.

Kuzma J. 2007.Moving forward responsibly: Oversight for the nanotechnology-biology interface. Journal of Nanoparticle Research V9 (1):165-182

Lee M-H, McClellan WJ, Candela J, Andrews D, and Biswas P. 2007.Reduction of nanoparticle exposure to welding aerosols by modification of the ventilation system in a workplace. Journal of Nanoparticle Research V9 (1):127-136.

Lin M, Wang Z, and Zhang D. 2007.Preparation of Orpiment Nanoparticles and Their Cytotoxic Effect on Cultured Leukemia K562 Cells. Journal of Nanoscience and Nanotechnology 7:496.

Maynard AD, Ku BK, Emery M, Stolzenburg M, and McMurry PH. 2007.Measuring particle size-dependent physicochemical structure in airborne single walled carbon nanotube agglomerates. Journal of Nanoparticle Research V9 (1):85-92.

Medina C, Santos-Martinez MJ, Radomski A, Corrigan OI, and Radomski MW. 2007.Nanoparticles: pharmacological and toxicological significance. Br J Pharmacol. 2007 Jan 22; [Epub ahead of print]

Morfeld P. 2007. Lung dosimetry and risk assessment of nanoparticles. Inhalation toxicology 19 (2):195; author reply 197-8.

Muller K, Skepper JN, Posfai M, Trivedi R, Howarth S, Corot C, Lancelot E, Thompson PW, Brown AP, and Gillard JH. 2007.Effect of ultrasmall superparamagnetic iron oxide nanoparticles (Ferumoxtran-10) on human monocyte-macrophages in vitro. Biomaterials 28 (9):1629-42.

Pulskamp K, Diabate S, and Krug HF. 2007. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicology letters 168 (1):58-74.

Rouse JG, Yang J, Ryman-Rasmussen JP, Barron AR, and Monteiro-Riviere NA. 2007. Effects of Mechanical Flexion on the Penetration of Fullerene Amino Acid-Derivatized Peptide Nanoparticles through Skin. Nano Lett. 7 (1):155-160.

Tang YJ, Ashcroft JM, Chen D, Min G, Kim CH, Murkhejee B, Larabell C, Keasling JD, and Chen FF. 2007.Charge-Associated Effects of Fullerene Derivatives on Microbial Structural Integrity and Central Metabolism. Nano Lett. 2007 Feb 9; [Epub ahead of print]

Teeguarden JG, Hinderliter PM, Orr G, Thrall BD, and Pounds JG. 2007. Particokinetics In Vitro: Dosimetry Considerations for In Vitro Nanoparticle Toxicity Assessments. Toxicological Sciences 95 (2):312.

Wang J, Zhou G, Chen C, Yu H, Wang T, Ma Y, Jia G, Gao Y, Li B, Sun J, Li Y, Jiao F, Zhao Y, and Chai Z. 2007. Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. 168 (2):176-185.

Wick P, Manser P, Limbach LK, Dettlaff-Weglikowska U, Krumeich F, Roth S, Stark WJ, and Bruinink A. 2007. The degree and kind of agglomeration affect carbon nanotube cytotoxicity. Toxicology letters 168 (2):121-31.

Worle-Knirsch JM, Kern K, Schleh C, Adelhelm C, Feldmann C, and Krug HF. 2007. Nanoparticulate Vanadium Oxide Potentiated Vanadium Toxicity in Human Lung Cells. Environ. Sci. Technol. 41 (1):331-336.

Yang K and Xing B. 2007. Desorption of polycyclic aromatic hydrocarbons from carbon nanomaterials in water. Environmental pollution (Barking, Essex 145 (2):529-37.